1
Golden Poison Frog
- Value (with unit)
- 0.002
- Additional Info
- LD50 mg/kg (mouse SC), native to Colombia

This ranking is meticulously compiled based on scientifically recognized Median Lethal Dose (LD50) data and potential lethal risk to humans. It covers a diverse range of animals, plants, and fungi known for their potent toxins. The list aims to educate the public on biological toxicity knowledge and safety awareness. Please note that specific values may vary by study, and data is for reference only.
The Golden Poison Frog (Phyllobates terribilis) reigns supreme as nature's ultimate biochemical weapon.
| Rank | Name | Value (with unit) | Additional Info |
|---|---|---|---|
| 1 | Golden Poison Frog | 0.002 | LD50 mg/kg (mouse SC), native to Colombia |
| 2 | Blue-ringed Octopus | 0.008 | LD50 mg/kg (mouse SC), contains tetrodotoxin |
| 3 | Inland Taipan | 0.025 | LD50 mg/kg (mouse SC), most toxic land snake |
| 4 | Belcher's Sea Snake | 0.044 | LD50 mg/kg (mouse SC), most toxic sea snake |
| 5 | Eastern Brown Snake | 0.053 | LD50 mg/kg (mouse SC), common venomous snake in Australia |
| 6 | Geography Cone | 0.05 | LD50 mg/kg (mouse IV), contains conotoxin |
| 7 | Box Jellyfish | 0.1 | LD50 mg/kg (estimated), tentacles contain potent venom |
| 8 | Destroying Angel | 0.1 | LD50 mg/kg (mouse IP), contains amatoxins |
| 9 | Pufferfish | 0.15 | LD50 mg/kg (mouse IP), organs contain tetrodotoxin |
| 10 | King Cobra | 0.3 | LD50 mg/kg (mouse SC), huge venom yield |
| 11 | Brazilian Wandering Spider | 0.5 | LD50 mg/kg (mouse IV), highly aggressive |
| 12 | Stonefish | 0.8 | LD50 mg/kg (mouse IV), dorsal fin spines highly venomous |
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